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Principal Scientist - Computer Aided Drug Design (CADD)

€negotiable | Belgium |  Regulatory Affairs, Pharmaceutical Company/Sponsor side |  Permanent  | Ref:889864

The Role

Principal Scientist - Computer Aided Drug Design (CADD) - Global Biopharma - Belgium - €negotiable

The Principal Scientist - Computer Aided Drug Design (CADD) will work alongside Computational and Medicinal Chemists in solving drug design challenges using computational & medicinal chemistry tools.

*This company are looking to interview via video and the onboarding process can occur remotely*


The Company

This is an exciting time to join an expanding, highly successful global biopharma based in their offices in Braine, Belgium. They have lots of exciting projects to work on within a fast paced, innovative environment.

  • Global biopharma at the forefront of what they do
  • Highly innovative company who are always open and promoting the use of new and advanced technology
  • Excellent support and facilities in order to support their Scientists
  • They have great relationships and collaborate with many CROs and Universities
  • High investment into cutting edge scientific research


The Role

The Principal Scientist - Computer Aided Drug Design (CADD) will be responsible for;

  • Ultimately solving drug design challenges using computational & medicinal chemistry tools
  • Critically interpret and propose compound designs
  • You will analyse project data, recognise aberrant results, and propose explanations
  • Using structure-based, ligand-based, machine learning/AI and other statistical modelling approaches, you will work in drug discovery projects to curate and analyse complex datasets and deliver solutions.
  • You will use your broad knowledge of and experience in challenges facing small molecule discovery



To apply for this role as a Principal Scientist - Computer Aided Drug Design (CADD) our client is hoping for someone with the following skills and experience;

  • You will have computational chemistry experience ideally within a pharma company
  • You have a PhD, or equivalent, in chemistry
  • A good understanding of the physical chemistry of intra- and inter-molecular interactions in protein-ligand complexes.
  • Excellent stakeholder management experience, being able to challenge and educate stakeholders from various functions
  • Working knowledge of issues within drug design related to physicochemical properties, ADME, safety & formulation.
  • Expertise in using and improving computational software; strong scientific computing and programming skills (e.g. Python, C , Java).
  • Ability to effectively interpret and communicate experimental results using advanced data analytics

What should you do next?

This Principal Scientist - Computer Aided Drug Design (CADD) role is one not to be missed; it encompasses the opportunity to work in a global biopharma who are at the forefront of their therapy areas. To discuss further, please submit your current CV.

Unless otherwise stated, if applying for a job within the European Union, you must ensure that you are already authorised to work there.

Carrot Pharma Recruitment Ltd acts as an Employment Business and an Employment Agency on behalf of our client in recruitment for this role.



Hayley Shayestehroo

Which team and area do you work/specialise in?

I work in the Regulatory Affairs team and recruit for Regulatory Affairs professionals at all levels within Pharma, Medical Devices companies and Regulatory Consultancies

What are some of the typical roles you cover?

I cover Regulatory Affairs positions at all levels within Pharma, Medical Devices and Regulatory Consultancies, these typically include;

Regulatory Affairs Associate jobs, Regulatory Affairs Executive jobs, Regulatory Affairs Senior Associate jobs, Regulatory Affairs Manager jobs, Regulatory Affairs Senior Manager jobs, Regulatory Affairs Director jobs, Regulatory Affairs Consultant jobs, Regulatory Writer jobs and Medical Writer jobs.

What are the hot issues in your sector currently?

Within Medical Devices it is the transition from MDD to MDR in May 2020. A lot of medical device companies are hiring Regulatory professionals to prepare their company for the transition

What’s makes you #DistinctlyDifferent?

I take pride in getting to know my candidates on a personal level as well as professional. Changing jobs is a big decision for most people so I like to ensure I am placing my candidates in a role that not only matches their career aspirations but also suits their personal situation and key motivations.


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